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Comparative Protein Structure Modelling using MODELLER
(1-Day, 3-3.5 Hour Intensive Workshop)
Quaxon Bio & IT Solutions, India is going to conduct it’s 60th international Virtual workshop on Comparative protein structure prediction on 17th Aug 2025.
Schedule Date: 17th Aug 2025
Time: 9 AM to 12 Noon Indian Standard Time
Kindly check the schedule time at your time zone or country by visiting this link
https://savvytime.com/converter
Key Takeaway
Complete practical oriented training.
Designed for beginner to advance level learners
Certificate for all participants
Study manual and video tutorial
Eligibility
Faculty, students, research scholars from all biological and related discipline (Biotechnology, pharmaceutical science, microbiology, bioinformatics and other allied areas) .Participants to use their own computer/laptop preferably with windows operating system
Importance of theme topic
Homology modeling, also known as comparative modeling, is considered one of the central and most widely used techniques for predicting the three-dimensional structure of proteins.
Knowledge of protein structure is crucial to understanding its function in various biological processes. Homology modeling has been one of the most frequently used theoretical methods for protein structure design in bioscience research over the past few decades. This in-silico based method is very cost-effective and consumes less time compared to experimental methods like X-ray crystallography.
In this workshop, participants will be introduced to the complete theoretical concept and practical steps of homology modeling of proteins, using the popular program Modeller. The session will cover basic homology modeling and advanced level “multi-template modeling.
Course Curriculum
Overview of the workshop objectives
Importance of protein structure prediction in biological research
Introduction to MODELLER software and its applications
Topics:
Basics of Protein Structure
Primary, secondary, tertiary structures
PDB file format overview
Principles of Comparative (Homology) Modelling
Concept of sequence–structure relationship
Steps in homology modelling
MODELLER Workflow
Template selection
Sequence alignment
Model building
Model evaluation & refinement
Key Applications & Limitations of MODELLER
Hands-on Session-1
Activities:
Template Identification
Modeller installation and set-up
Using BLASTp against PDB database
Choosing best template based on sequence identity and resolution
Sequence Alignment
Using MODELLER’s script
Alignment file format creation
Hands-on Session Part 2: Model Building & Evaluation
Activities:
Model Generation
Running MODELLER
Model Evaluation
DOPE score interpretation
Visual inspection in PyMOL/Chimera
Selection of Best Model
Loop refinement using MODELLER
Q&A + Wrap-Up
Recap of workflow
Common troubleshooting tips
Suggested resources for further learning
Deliverables for Participants
- Session recording will be shared for further practice
- PDF handout of MODELLER workflow & commands
- Sample dataset (target sequence + template PDB file)
- All scripts used in the session
- LinkedIn Sharable E-Certificate
Steps to Participate
Step-1: Make the payment and Take the screenshot/note transaction number
Participation Fee (For Indians)
B.Sc./MSc students: Rs.450/-
PhD/Research Scholar: Rs.500/-
Faculty/PDF/other working person: Rs.550/-
Payment Link for Indians https://rzp.io/rzp/F0FeQQVq
Participation Fee (For International Participants): $12/-
Payment link for international participants: https://paypal.me/Workshop334
Step-2: Must complete registration by filling this form
About Us :
Quaxon Bio & IT Solutions is a dynamic startup, officially registered with the Ministry of Micro, Small, and Medium Enterprises, Government of India. We serve as the bridge between industry and academia, fostering knowledge transformation and cultivating a workforce poised for the future of technology. Our mission is to provide education in the realm of cutting-edge scientific advancements, making it accessible to individuals worldwide. With students spanning across 41 countries, in addition to our presence in India, we stand proud of our commitment to delivering high-quality technical education at affordable rates, ensuring that everyone can partake in the journey of innovation and growth.
WhatsApp/Call us +91-96925 21875
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Write to us support@qbiits.org or to quaxonbiits@gmail.com